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«POKAZATELI MINERAL'NOY PLOTNOSTI KOSTNOY TKANI I UROVEN' 25-GIDROKSIVITAMINA D SYVOROTKI KROVI U ZhENShchIN REPRODUKTIVNOGO VOZRASTA
- Authors: KARONOVA T.L.
- Issue: Vol 14, No 3 (2011)
- Pages: 11-13
- Section: Articles
- URL: https://osteo-endojournals.ru/osteo/article/view/4052
- DOI: https://doi.org/10.14341/osteo2011311-13
- Cite item
Abstract
We evaluated the effect of serum Vitamin D level on bone mineral density in 270 women of reproductive age. Insufficiency and deficiency of vitamin D were found in 86.8% of women regardless of the season when the examination was performed. The DXA results showed that every 5th woman had a decreased BMD. Correlation analysis revealed a significant direct relationship between serum vitamin D level and BMD in women up to 40 years old (r=0,48, p=0,04), whereas in those over 40 years this relationship could not be seen. Additional studies are required for further assessment of vitamin D role in bone remodeling
About the authors
T. L. KARONOVA
kandidat meditsinskikh nauk, assistent kafedry fakul'tetskoy terapii SPbGMU im. I. P. Pavlova, starshiy nauchnyy sotrudnik
References
- Каронова Т.Л., Баженова Е.А., Михеева Е.П. и соавт. Роль 25-гидрокси витамина Д3 в регуляции углеводного обмена у женщин с избыточным весом// Бюллетень Федерального Центра Сердца, Крови и Эндокринологии им. В.А.Алмазова.-2010.- №5.-С.35-38.
- Остеопороз: диагностика, профилактика и лечение (клинические рекомендации)/ Под ред. О.М.Лесняк, Л.И.Беневоленской.-2-е изд., перераб. и доп.-М.: ГЭОТАР-Медиа, 2009.-272 С.
- Adams J.S., Hewison M. Update in vitamin D.// J. Clin. Endocrinol.& Metab., 2010. - V. 95. - P. 471-478.
- Arunabh S., Pollack S., Yeh J., Aloia JF. Body fat content 25-hydroxyvitamin D level in healthy women //J Clin Endocrinol Metab.-2003.-V.88(1).-P.157-161.
- Barton D. Vitamin D. — 2008. — www.cancernetwork.com/display/ article
- Bikle D. Vitamin D: Prodaction, metabolism, and mechanisms of action.-2009.-www.endotext.org/parathyroid3
- Bischoff-Ferrari HA., Dawson-Hughes B., Willett W.C. et al. Effect of vitamin D on falls: a meta-analysis // Journal of the American Medical Association. -2004.- V.291.-P.1999-2006.
- Bischoff-Ferrari HA., Kiel D.P., Dawson-Hughes B.et al. Dietary calcium and serum 25-hydroxyvitamin D status in relation to BMD among U.S. Adults //J Bone Miner Res.-2009.-V.24.-P.935-942.
- Boonen S., Bischoff-Ferrari H.A., Cooper C. Addressing the musculoskeletal componets of fracture risk with calcium and vitamin D: a rewiew of the evidence // Calcified Tissue International.-2006.-V.78.-P257-270.
- Bouillon R., Carmeliet G., Verlinden L. et.al. Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice / Endocrine Reviews, 2008. - V. 29(6). - Р 726-776.
- Cauley J.A., Lacroix A.Z., Wu L. et al. Serum 25-hydroxyvitamin D concetrationandriskforhipfractures//Ann Intern Med.-2008.-V.149.-P.242-250.
- Chapuy M.C., Arlot M.E., Duboeuf F. et al., Vitamin D3 and calcium to prevent hit fractures in the elderly women // New England Journal of Medicine-1992.-V.327.-P1637-1642.
- Heaney R.P. The importance of calcium intake for lifelong skeletal health // Calcified Tissue International.-2002.-V.70.-P.70-73.
- Holick M.F. High prevalence ofvitamin D inadequacy and implications for health //Mayo Clin Proc., 2006. - V. 81(3). - P. 353-373.
- Holick M.F. Vitamin D Deficiency / New Engl. J. Med., 2007. - V. 357(3). — P.266-281.
- Lindsay R. Estrogens for the prevention of osteoporosis./ Lindsay R., Kleerekoper M.// Drugs for osteoporosis.// Lindsay R.-2005.-P.1-27.
- Lips P. Vitamin D deficiency and secondary hyperparathyreoidism in the elderly: concequences for bone loss and fractures and therapeutic implications //Endocrine reviews-2001.-V.22.-P.477-501.
- Lips. P., Bouilon R., Van Schoor NM. et al. Reducing fracture risk with calcium and vitamin D // Clinical Endocrinology -2010.-V.73.- P277-285.
- Kremer R., Campbell PP., Reinhardt T., Gilsanz V. Vitamin D status and its reationship to body fat, final height and peak bone mass in young women //J Clin Endocrinol Metab.-2009.-V.94.-P.67-73.
- Van Schoor NM., Visser M., Pluijm SM. et al. Vitamin D deficiency as a risk factor for osteoporotic fractures // Bone-2008.-V.42.-P.260-266.
- Wortsman J., Matsuoka L.Y., Chen T.C., Lu Z., Holick MF. Decreased bioavailability ofvitamin D in obesity// Am J Clin Nutr.- 2000.- V.72.-P690-693.
